Modified FGF-21 polypeptides comprising an internal deletion and uses thereof
作者： Dasa Lipovsek , Ray Camphausen , John Krupinski , Timothy P. Reilly , Paul E. Morin
DOI:
关键词: Molecular biology 、 Amino acid 、 Fibrosis 、 Fibroblast growth factor 、 Biochemistry 、 Peptide 、 Biology
摘要: Modified FGF-21 polypeptides and uses thereof are provided, for example, the treatment of diseases associated with fibrosis. disclosed that contain an internal deletion optionally replacement peptide, modified at least one non-naturally-encoded amino acid, and/or fused to a fusion partner.
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