Anti-siglec-15 antibodies
作者： Matthew Stuible , Anna N. Moraitis , Traian Sulea , Gilles Bernard Tremblay , Mario Filion
DOI:
关键词: Chemistry 、 Antibody 、 Molecular biology 、 Antigen binding 、 SIGLEC 、 Bone resorption
摘要: Antibodies and antigen binding fragments that specifically binds to Siglec-15 are described herein. These antibodies or may have the ability of inhibiting differentiation osteoclasts and/or bone resorption activity osteoclasts. Compositions cells expressing anti-Siglec-15 also disclosed herewith. Anti-Siglec-15 be useful for treatment loss, diseases. Methods detection diagnosis loss bone-related diseases described.
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