The Ischemic Penumbra: Identification, Evolution and Treatment Concepts

摘要: The concept of the ischemic penumbra is an important one for both basic investigators cerebral ischemia and clinicians who treat stroke patients. has been defined in a variety ways, but most clinically relevant definition that portion territory still potentially salvageable, if appropriate treatment given. Currently, three main challenges persist those interested concept: how can this region be accurately identified patients, what mechanisms cell death are progression from towards irreversible injury therapeutic modalities likely to impede development infarction? Much information regarding each these topics become available recently will focus paper.