Alternative calibration approaches to compensate the effect of co-extracted matrix components in liquid chromatography–electrospray ionisation tandem mass spectrometry analysis of pesticide residues in plant materials

摘要: The aim of this study was to evaluate the applicability different calibration approaches in a multi- and single-residue analysis modern pesticides plant matrices using liquid chromatography-electrospray mass spectrometry (HPLC-ESI-MS). In first set experiments determination eight representing groups polar/unstable (carbamates, benzimidazoles, azoles, benzoylphenylurea) apple samples performed. trueness precision data obtained by using: (i) external solvent standard calibration, (ii) matrix-matched (iii) echo-peak internal compared. last mentioned method is novel technique providing possibility inject same identity as target analyte, so that its retention time close analyte from sample. According expectation, when results were under- or overestimated due suppression enhancement analyte's signal matrix components. On other hand with use accurate obtained. With comparable those for six out pesticides. second experiment we used overcome problem response instability chlormequat pear concentrate samples. As an provided monitoring decrease during analytical sequence compensate relating sample peak area relatively standard.