Higher preablative serum thyroid-stimulating hormone level predicts radioiodine ablation effectiveness in patients with differentiated thyroid carcinoma.

摘要: Introduction Radioiodine ablation of remnant thyroid tissue is an important adjuvant therapy differentiated carcinoma (DTC) after thyroidectomy. Elevated serum thyroid-stimulating hormone (TSH) level necessary for successful ablation. The optimum TSH radioiodine well-DTC is, however, yet to be defined. We aimed determine whether higher will result in a better rate complete using iodine-131 (131I) following initial Patients and methods A total 109 patients with cancer were divided into four treatment groups on the basis levels. They followed up from 6 12 months stimulated thyroglobulin diagnostic whole-body scan radioactive iodine 131I early response. Results Sixty-four had papillary carcinoma, whereas 45 follicular carcinoma. An excellent response was observed 66.7% more than 90 μIU/ml, 72.2% group 60–89 μIU/ml, 48.5% when 30–59 μIU/ml 26.7% less 30 μIU/ml (P=0.002). Conclusion Higher preablative predicts treated