Computer simulation of cerebellar information processing.

摘要: Although many functions have been ascribed to the cerebellum, uniformity of its synaptic organization suggests that a single, characteristic computation may be common all. Computer simulations are useful in examining this cerebellar computation, as they inherently address function at level information processing. Progress is facilitated by factors make cerebellum particularly amenable such analysis. We review progress from two contrasting approaches. Top-down begin with hypotheses about computational mechanisms and then ask how might operate within cerebellum. Bottom-up attempt build representation reflects known cellular components accurately possible. describe recent advances these approaches leading an understanding what processes neurons synapses accomplish task.