Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice
作者： Lorenzo Federico , Liping Yang , Jason Brandon , Manikandan Panchatcharam , Hongmei Ren
DOI: 10.1371/JOURNAL.PONE.0198063
关键词: Sphingolipid 、 Lipid metabolism 、 Chemistry 、 Ceramide 、 Endocrinology 、 Internal medicine 、 Lipid phosphatase activity 、 Adipocyte 、 Sphingosine 、 Phosphatidate phosphatase 、 Adipogenesis
摘要: … role of LPPs in adipocyte lipid metabolism and signaling we made mice with adipocyte-targeted inactivation of LPP3 encoded by the Plpp3(Ppap2b) gene. Adipocyte LPP3 deficiency …
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