The Use of an α-Cyclodextrin Mobile Phase in the Thin-Layer Chromatographic Separation of Ortho, Meta, and Para Substituted Phenols
作者： Walter G. Burkert , Charlton N. Owensby , Willie L. Hinze
DOI: 10.1080/01483918108059604
关键词: Thin layer chromatographic 、 Phenols 、 Organic solvent 、 Cyclohexaamylose 、 Cyclodextrin 、 Polyamide 、 Organic chemistry 、 Chemistry 、 Chromatography 、 Phase (matter) 、 Aqueous solution
摘要: Abstract An aqueous solution of α-cyclodextrin (cyclohexaamylose) is demonstrated to be a very effective mobile phase in thin-layer chromatographic separations. The behaviors twenty-six substituted phenolic and naphtholic compounds using polyamide stationary sheets are described. Rf values were found dependent upon both the structural features concentration phase. A possible mechanism that accounts for observed behavior presented. advantages disadvantages over traditional pure or mixed organic solvent systems typically employed discussed.
sci-hub.se 参考文章(27)
Halina Szumilo, Edward Soczewinski, Investigations on the mechanism and selectivity of chromatography on thin layers of polyamide Journal of Chromatography A. ,vol. 94, pp. 219- 227 ,(1974) , 10.1016/S0021-9673(01)92369-6
E. Soczewiński, W. Gołkiewicz, H. Szumiło, A simple molecular model of adsorption chromatography Journal of Chromatography A. ,vol. 45, pp. 1- 13 ,(1969) , 10.1016/S0021-9673(01)86177-X
Kazuaki Harata, Crystal structure of the cyclohexaamylose-p-iodophenol complex Carbohydrate Research. ,vol. 48, pp. 265- 270 ,(1976) , 10.1016/S0008-6215(00)83222-X
Willie L. Hinze, Daniel W. Armstrong, Thin Layer Chromatographic Separation of Ortho, Meta, and Para Substituted Benzoic Acids and Phenols with Aqueous Solutions of α-Cyclodextrin Analytical Letters. ,vol. 13, pp. 1093- 1104 ,(1980) , 10.1080/00032718008082575
Wolfgang Wildenhain, Günter Henseke, Gert Bienert, Dünnschichtchromatographie von 4-Acetyl-2-nitrophenyl-Derivaten phenolischer Verbindungen Journal of Chromatography A. ,vol. 45, pp. 158- 160 ,(1969) , 10.1016/S0021-9673(01)86198-7
N. Irving Sax, Dangerous properties of industrial materials ,(1957)
J. Ościk, G. Chojnacka, Investigation of the chromatographic process by the correlation between the RM-values in adsorption and partition chromatography Chromatographia. ,vol. 7, pp. 708- 712 ,(1974) , 10.1007/BF02269202
Daniel W. Armstrong, Susan J. Henry, Use of an Aqueous Micellar Mobile Phase for Separation of Phenols and Polynuclear Aromatic Hydrocarbons via HPLC Journal of Liquid Chromatography & Related Technologies. ,vol. 3, pp. 657- 662 ,(1980) , 10.1080/01483918008060181
R.L. Cooper, K.C. Wheatstone, The determination of phenols in aqueous effluents Water Research. ,vol. 7, pp. 1375- 1384 ,(1973) , 10.1016/0043-1354(73)90014-6
Raymond J. Bergeron, Michael Almy Channing, George J. Gibeily, David M. Pillor, Disposition requirements for binding in aqueous solution of polar substrates in the cyclohexaamylose cavity Journal of the American Chemical Society. ,vol. 99, pp. 5146- 5151 ,(1977) , 10.1021/JA00457A040