THE PRURITUS OF CHOLESTASIS: Evolving Pathogenic Concepts Suggest New Therapeutic Options

作者: Nora V. Bergasa , E. Anthony Jones

DOI: 10.1016/S1089-3261(05)70014-3

关键词: GastroenterologyInternal medicineLiver transplantationCholestasisMedicineIntensive care medicine

摘要: "Like lying on a bed of cactus" is how one patient with the pruritus cholestasis described her symptoms. 50 This form remains most challenging management problems for gastroenterologists and hepatologists because its cause unknown conventional treatments are not consistently effective. The can be so severe that it may an indication liver transplantation even in absence overt hepatocellular failure. 27 Severe intractable constitutes medical emergency patients chronic unrelieved become suicidal.

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