Insulin-like growth factor 1 enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK and JNK MAPK pathways

作者: Yan Yu , Jinquan Mu , Zhipeng Fan , Gang Lei , Ming Yan

DOI: 10.1007/S00418-011-0908-X

关键词: Periodontal ligament stem cellsGrowth factorStem cellMAPK/ERK pathwayTransplantationRUNX2ChemistryOsteoblastCell biologyPeriodontal fiberImmunology

摘要: Insulin-like growth factor 1 (IGF-1) is a potent mitogenic protein which can enhance the osteogenic differentiation of periodontal ligament (PDL) fibroblasts. However, it remains …

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