Evaluation of deleted in malignant brain tumors 1 (DMBT1) gene expression in bladder carcinoma cases: preliminary study.
作者： Yavuz Dodurga , Cigir Biray Avci , Sunde Yilmaz , Z. Ozlem Dogan , Zehra Kesen
DOI: 10.3109/1354750X.2011.620627
关键词: Gene expression 、 Carcinoma 、 Transitional cell carcinoma 、 Mrna level 、 DMBT1 gene 、 Urinary bladder 、 Bladder cancer 、 Medicine 、 Significant difference 、 Pathology
摘要: This study was undertaken to evaluate the expression of DMBT1 in bladder cancer and its correlation with clinico-pathological parameters analyzed carcinoma patients. We investigated 56 paraffin embedded specimens transitional cell urinary bladder. assessed gene at mRNA level by RT-PCR. Our results show 100% samples. Due this preliminary results; compared tumor grade, a significant difference detected between grade 1 3 (p = 0.028). The down-regulation carcinomas suggests possible role cancer.
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