Aloe-emodin induces autophagy and apoptotic cell death in non-small cell lung cancer cells via Akt/mTOR and MAPK signaling.

作者: Fengge Shen , Chunpo Ge , Peng Yuan

DOI: 10.1016/J.EJPHAR.2020.173550

关键词: Modern medicinePI3K/AKT/mTOR pathwayLung cancerCytotoxic T cellProtein kinase BApoptosisAutophagyCancer researchChemistryReactive oxygen species

摘要: Lung cancer has a relatively poor prognosis, and the clinical efficacy of targeted drugs remains unsatisfactory. Therefore, the search for safe and efficient novel antitumor drugs has …

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