Kinetics of carrier-mediated ion transport across lipid bilayer membranes

作者: P. Läuger , G. Stark

DOI: 10.1016/0005-2736(70)90251-8

关键词: ConductanceIonModel lipid bilayerKineticsBiophysicsIon transporterLipid bilayerMembraneAnalytical chemistryLipid bilayer phase behaviorChemistryCell biologyBiochemistry

摘要: Abstract A theoretical treatment of the electrical conductance and tracer permeability lipid bilayer membranes in presence macrocyclic ion carriers is given. The analysis based on assumption that complex between carrier formed membrane-solution interface. translocation across membrane described as a transport over an activation energy barrier. It shown some information rate constants may be obtained from existing measurements. For instance, current voltage characteristic lecithin monactin indicates rate-determining step interior membrane.

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