Comparative pathogenicity of four strains of Aleutian disease virus for pastel and sapphire mink.

摘要: Information was sought on the comparative pathogenicity of four North American strains (isolates) Aleutian disease virus for royal pastel (a non-Aleutian genotype) and sapphire (an mink. The (Utah-1, Ontario [Canada], Montana, Pullman [Washington]), all mink origin, were inoculated intraperitoneally intranasally in serial 10-fold dilutions. As indicated by appearance specific antibody (counterimmunoelectrophoresis test), readily infected both color phases mink, equally pathogenic Not strains, however, regularly caused Infection with Utah-1 strain invariably led to fatal disease. nearly as often. strain, contrast, almost never Montana this phase between these extremes. These findings emphasize need distinguish infection when are exposed virus. distinction has important implications understanding natural history ranch