Reaction of 6‐phenyl‐2‐(p‐toluenesulfonyl)‐3(2H)pyridazinone with grignard reagents
作者： Choji Kashima , Akira Katoh , Miyuki Fukasawa , Yoshimori Omote
关键词: Grignard reagent 、 Quenching (fluorescence) 、 Nuclear magnetic resonance spectroscopy 、 Reaction conditions 、 Organic chemistry 、 Reagent 、 Chemistry 、 Aliphatic compound 、 Alcohol
摘要: 6-Phenyl-2-(p-toluenesulfonyl)-3(2H)pyridazinone (I) reacted with Grignard reagents to give 5-substituted 4,5-dihydro-3(2H)pyridazinones II and two types of dihydropyridazines, III IV. The ratio II, III, IV was sensitively dependent on the reaction conditions. Further, by quenching mixture alcohol, ring-opened product VII mainly isolated.
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