作者: Brian Johnson , Mark Hallett , Semyon Slobounov
DOI: 10.1212/WNL.0000000000001968
关键词: Neuroimaging 、 Saccade 、 Asymptomatic 、 Magnetic resonance imaging 、 Functional neuroimaging 、 Eye movement 、 Concussion 、 Psychology 、 Physical medicine and rehabilitation 、 Young adult
摘要: Objective: To expand on our previous study by performing a follow-up testing session in the subacute phase of injury for participants recently diagnosed with concussion. Methods: A battery oculomotor tests were administered to 30 days postconcussion while simultaneous fMRI was performed. Results: Three 7 tasks (antisaccade, self-paced saccade, and memory-guided saccade) showed significant differences between concussed group compared normal volunteers. However, performance these 3 did show improvement from acute injury. The analysis revealed brain activation patterns volunteers, still demonstrating increased larger areas activation. Similar performance, that at postinjury, more closely mirrored volunteer following insult. Conclusions: Even despite being clinically asymptomatic, advanced techniques are able detect subtle lingering alterations brain. Therefore, progressive neuroimaging such as conjunction assessment may be beneficial clinical management