The role of uric acid in heart failure

作者: Hernán Alcaíno , Douglas Greig , Pablo Castro , Hugo Verdejo , Rosemarie Mellado

DOI: 10.4067/S0034-98872011000400014

关键词: Uric acidAntioxidantAdipose tissueMedicineInternal medicineEndocrinologyPurine metabolismIntracellularHeart failureDiseasePathophysiology

摘要: Complications and mortality of heart failure are high, despite the availability several forms treatment. Uric acid, end product purine metabolism would actively participate in pathophysiology failure. However, there is no consensus about its action cardiovascular disease. Serum uric acid have a protective antioxidant activity. This could help to reduce or counteract processes that cause appear as result these properties vanish intracellular environment highly hydrophobic areas such atherosclerotic plaques adipose tissue. review discusses paradoxical

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