Small Molecule Inhibitors Targeting New Targets of Protein-Protein Interactions

摘要: Targeting protein-protein interactions by small molecule compounds is challenging; however, exciting achievements have been made over the past decade. New targets of PPIs were identified, and lots modulators developed. In this chapter, we make a brief review research into their inhibitors. We focus on progress in some new involving biological processes such as epigenetic modification, ubiquitin-mediated protein degradation, immune response, RTK signaling pathway, copper transport. These case studies may provide researchers with basic overview area. Several other promising are also discussed herein.