The in vivo antineoplastic and therapeutic efficacy of troxerutin on rat preneoplastic liver: biochemical, histological and cellular aspects.

作者: Nisha Susan Thomas , Kiran George , Sivaranjani Arivalagan , Vijay Mani , Aktarul Islam Siddique

DOI: 10.1007/S00394-016-1275-0

关键词: Oxidative stressBioflavonoidCell growthRutinPharmacologyFibrosisIn vivoTroxerutinDrug metabolismBiology

摘要: Purpose Troxerutin (TXER), a trihydroxyethylated derivative of the natural bioflavonoid rutin, abundantly found in tea, various fruits and vegetables, is known to exhibit ample pharmacological properties. In present investigation, we examined antineoplastic, therapeutic efficacy furthermore possible mechanisms action TXER against NAFLD/NASH progression hepatocarcinogenesis.

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