Involvement of Lipids in Alzheimer's Disease Pathology and Potential Therapies.
作者： Hannah Chew , Victoria A. Solomon , Alfred N. Fonteh
关键词: Blood–brain barrier 、 Lipid Transport 、 Pathology 、 Disease 、 Inflammation 、 Mitochondrion 、 Amyloid precursor protein 、 Lipid metabolism 、 Medicine 、 Apolipoprotein E
摘要: Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy function as well as the most common pathological conditions of the brain. Demographic …
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Bart P.F. Rutten, Harry W.M. Steinbusch, Hubert Korr, Christoph Schmitz, Antioxidants and Alzheimer's disease: from bench to bedside (and back again). Current Opinion in Clinical Nutrition and Metabolic Care. ,vol. 5, pp. 645- 651 ,(2002) , 10.1097/00075197-200211000-00006
M. Renuka Prasad, Mark A Lovell, Mustafa Yatin, Harbhajan Dhillon, William R. Markesbery, Regional Membrane Phospholipid Alterations in Alzheimer's Disease Neurochemical Research. ,vol. 23, pp. 81- 88 ,(1998) , 10.1023/A:1022457605436
Susumu Ando, Yasukazu Tanaka, Yuriko Toyoda ( Ono), Kazuo Kon, Turnover of Myelin Lipids in Aging Brain Neurochemical Research. ,vol. 28, pp. 5- 13 ,(2003) , 10.1023/A:1021635826032
Jane E. Preston, N. Joan Abbott, David J. Begley, Transcytosis of macromolecules at the blood-brain barrier. Advances in pharmacology. ,vol. 71, pp. 147- 163 ,(2014) , 10.1016/BS.APHA.2014.06.001
Thomas J. Montine, C. N. Bassett, Lipoproteins and lipid peroxidation in Alzheimer's disease. Journal of Nutrition Health & Aging. ,vol. 7, pp. 24- 29 ,(2003)
Christiane Reitz, Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations. Journal of Alzheimer's Disease. ,vol. 30, ,(2012) , 10.3233/JAD-2011-110599
Jun-Feng Wang, Rui Lu, Yi-Zheng Wang, Regulation of β cleavage of amyloid precursor protein. Neuroscience Bulletin. ,vol. 26, pp. 417- 427 ,(2010) , 10.1007/S12264-010-0515-1
Charles N. Serhan, Novel Lipid Mediators and Resolution Mechanisms in Acute Inflammation: To Resolve or Not? American Journal of Pathology. ,vol. 177, pp. 1576- 1591 ,(2010) , 10.2353/AJPATH.2010.100322
Cheng-Xin Gong, Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal, Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation. Journal of Alzheimer's Disease. ,vol. 9, pp. 1- 12 ,(2006) , 10.3233/JAD-2006-9101
Alfred N. Fonteh, Cora Ormseth, Jiarong Chiang, Matthew Cipolla, Xianghong Arakaki, Michael G. Harrington, Sphingolipid Metabolism Correlates with Cerebrospinal Fluid Beta Amyloid Levels in Alzheimer’s Disease PLOS ONE. ,vol. 10, pp. e0125597- ,(2015) , 10.1371/JOURNAL.PONE.0125597