BMP signalling in skeletal development, disease and repair
作者： Valerie S Salazar , Laura W Gamer , Vicki Rosen , None
关键词: Bone morphogenetic protein 7 、 Pathology 、 Bone morphogenetic protein 2 、 Cartilage 、 Medicine 、 Bone regeneration 、 Bone morphogenetic protein 、 Bone morphogenetic protein 4 、 Endochondral ossification 、 Cell biology 、 Metabolic bone disease
摘要: Since the identification in 1988 of bone morphogenetic protein 2 (BMP2) as a potent inducer of bone and cartilage formation, BMP superfamily signalling has become one of the most heavily investigated topics in vertebrate skeletal biology. Whereas a large part of this research has focused on the roles of BMP2, BMP4 and BMP7 in the formation and repair of endochondral bone, a large number of BMP superfamily molecules have now been implicated in almost all aspects of bone, cartilage and joint biology. As modulating BMP …
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researchgate.net 参考文章(222)
Susumu Itoh, Peter ten Dijke, Negative regulation of TGF-β receptor/Smad signal transduction Current Opinion in Cell Biology. ,vol. 19, pp. 176- 184 ,(2007) , 10.1016/J.CEB.2007.02.015
Mihael H. Polymeropoulos, Susan E. Ide, Trish Magyari, Clair A. Francomano, Brachydactyly Type C Gene Maps to Human Chromosome 12q24 Genomics. ,vol. 38, pp. 45- 50 ,(1996) , 10.1006/GENO.1996.0590
Ingo Grafe, Tao Yang, Stefanie Alexander, Erica P Homan, Caressa Lietman, Ming Ming Jiang, Terry Bertin, Elda Munivez, Yuqing Chen, Brian Dawson, Yoshihiro Ishikawa, Mary Ann Weis, T Kuber Sampath, Catherine Ambrose, David Eyre, Hans Peter Bächinger, Brendan Lee, Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta Nature Medicine. ,vol. 20, pp. 670- 675 ,(2014) , 10.1038/NM.3544
Sonja A. Rasmussen, Frederick R. Bieber, Beryl R. Benacerraf, Ralph S. Lachman, David L. Rimoin, Lewis B. Holmes, Epidemiology of osteochondrodysplasias: Changing trends due to advances in prenatal diagnosis American Journal of Medical Genetics. ,vol. 61, pp. 49- 58 ,(1996) , 10.1002/(SICI)1096-8628(19960102)61:1<49::AID-AJMG10>3.0.CO;2-W
Michael O. Baffi, Erin Slattery, Philip Sohn, Harold L. Moses, Anna Chytil, Rosa Serra, Conditional deletion of the TGF-β type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones Developmental Biology. ,vol. 276, pp. 124- 142 ,(2004) , 10.1016/J.YDBIO.2004.08.027
Luitgard M Graul-Neumann, Alexandra Deichsel, Ulrike Wille, Naseebullah Kakar, Randi Koll, Christian Bassir, Jamil Ahmad, Valerie Cormier-Daire, Stefan Mundlos, Christian Kubisch, Guntram Borck, Eva Klopocki, Thomas D Mueller, Sandra C Doelken, Petra Seemann, Homozygous missense and nonsense mutations in BMPR1B cause acromesomelic chondrodysplasia-type Grebe European Journal of Human Genetics. ,vol. 22, pp. 726- 733 ,(2014) , 10.1038/EJHG.2013.222
B. Shu, M. Zhang, R. Xie, M. Wang, H. Jin, W. Hou, D. Tang, S. E. Harris, Y. Mishina, R. J. O'Keefe, M. J. Hilton, Y. Wang, D. Chen, BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development Journal of Cell Science. ,vol. 124, pp. 3428- 3440 ,(2011) , 10.1242/JCS.083659
D. A. Stafford, L. J. Brunet, M. K. Khokha, A. N. Economides, R. M. Harland, Cooperative activity of noggin and gremlin 1 in axial skeleton development Development. ,vol. 138, pp. 1005- 1014 ,(2011) , 10.1242/DEV.051938
Ana Campos-Xavier, Jorge M. Saraiva, Ravi Savarirayan, Alain Verloes, Josué Feingold, Laurence Faivre, Arnold Munnich, Martine Le Merrer, Valérie Cormier-Daire, Phenotypic variability at the TGF-β1 locus in Camurati-Engelmann disease Human Genetics. ,vol. 109, pp. 653- 658 ,(2001) , 10.1007/S00439-001-0644-8
Petra Seemann, Anja Brehm, Jana König, Carsten Reissner, Sigmar Stricker, Pia Kuss, Julia Haupt, Stephanie Renninger, Joachim Nickel, Walter Sebald, Jay C. Groppe, Frank Plöger, Jens Pohl, Mareen Schmidt-von Kegler, Maria Walther, Ingmar Gassner, Cristina Rusu, Andreas R. Janecke, Katarina Dathe, Stefan Mundlos, Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN PLoS Genetics. ,vol. 5, pp. e1000747- ,(2009) , 10.1371/JOURNAL.PGEN.1000747