Immune privilege or inflammation? Insights into the Fas ligand enigma.

作者: Joe O'Connell , Aileen Houston , Michael W. Bennett , Gerald C. O'Sullivan , Fergus Shanahan

DOI: 10.1038/85395

关键词: Fas ligandRNAImmunologyBiologyFas Ligand ProteinImmune privilegeInflammation

摘要: Fas ligand (FasL) has become an enigmatic molecule: some evidence indicates that it contributes to immune privilege in tissues and tumors, whereas other data demonstrates FasL can elicit inflammation. New findings may begin reconcile the paradoxical effects of FasL.

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