Timing and genetic rapport between growth in skeletal maturity and height around puberty: similarities and differences between girls and boys.
作者： D Z Loesch , R M Huggins , J L Hopper , E Rogucka
DOI:
关键词: Biology 、 Skeletal maturity 、 Skeletal maturation 、 Body height 、 Maturity (psychological) 、 Twin study 、 Internal medicine 、 Sex characteristics 、 Demography 、 Genetic covariance 、 Growth velocity 、 Endocrinology
摘要: We have analyzed longitudinal twin data by using a multivariate normal model to identify and quantify genetic effects over time on two main aspects of growth, height skeletal maturity. The largest contribution the variance in both maturity coincided with respective ages peak growth velocity. highest covariance between these traits age greatest acceleration height. These findings imply existence regulatory or structural genes that influence also found sex differences rapport velocities for are consistent predominant role estrogen accelerating maturation females, additional mechanisms males which may promote independently gonadal steroids.
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