A DNA nanomachine induced by single-walled carbon nanotubes on gold surface
作者： Chao Zhao , Yujun Song , Jinsong Ren , Xiaogang Qu
DOI: 10.1016/J.BIOMATERIALS.2008.12.034
关键词: Nucleic acid thermodynamics 、 A-DNA 、 Materials science 、 DNA 、 Biosensor 、 Nanotechnology 、 Gel electrophoresis 、 Circular dichroism 、 Surface plasmon resonance 、 Biophysics 、 G-quadruplex
摘要: Single-walled carbon nanotubes (SWNTs) can selectively induce human telomeric i-motif DNA formation at pH 7.0. Based on this property, we design a nanomachine induced by SWNTs gold surface. The motor is G-quadruplex DNA. reversible hybridization between the and its complementary be modulated without changing solution pH. Up to now, our knowledge, there no report show that or detect Our work may provide new concept for designing an SWNT-induced detection of structure hybridization, conformational transition have been characterized surface in fluorescence confocal microscopy, circular dichroism, melting gel electrophoresis. folding unfolding kinetics were studied Fourier transform-surface plasmon resonance (FT-SPR). All these results indicate efficiently reversibly. Therefore will insights into application nanodevice under physiological conditions.
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Nina Berova, Robert W. Woody, 香爾 中西, Circular Dichroism: Principles and Applications ,(1994)
David G Myszka, Kinetic, equilibrium, and thermodynamic analysis of macromolecular interactions with BIACORE. Methods in Enzymology. ,vol. 323, pp. 325- 340 ,(2000) , 10.1016/S0076-6879(00)23372-7
S.K. Brahmachari, P. Balagurumoorthy, Structure and stability of human telomeric sequence. Journal of Biological Chemistry. ,vol. 269, pp. 21858- 21869 ,(1994) , 10.1016/S0021-9258(17)31882-3
Sander J. Tans, Alwin R. M. Verschueren, Cees Dekker, Room-temperature transistor based on a single carbon nanotube Nature. ,vol. 393, pp. 49- 52 ,(1998) , 10.1038/29954
Pulickel M. Ajayan, Otto Z. Zhou, Applications of Carbon Nanotubes cnem. ,vol. 80, pp. 391- 425 ,(2001) , 10.1007/3-540-39947-X_14
S. Boussaad, N. J. Tao, R. Zhang, T. Hopson, L. A. Nagahara, In situ detection of cytochrome c adsorption with single walled carbon nanotube deviceElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b302681g/ Chemical Communications. ,vol. 3, pp. 1502- 1503 ,(2003) , 10.1039/B302681G
N. W. Shi Kam, M. O'Connell, J. A. Wisdom, H. Dai, Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 11600- 11605 ,(2005) , 10.1073/PNAS.0502680102
X. Li, Y. Peng, J. Ren, X. Qu, Carboxyl-modified single-walled carbon nanotubes selectively induce human telomeric i-motif formation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 19658- 19663 ,(2006) , 10.1073/PNAS.0607245103
Linette M. Demers, Chad A. Mirkin, Robert C. Mucic, Robert A. Reynolds, Robert L. Letsinger, Robert Elghanian, Garimella Viswanadham, A Fluorescence-Based Method for Determining the Surface Coverage and Hybridization Efficiency of Thiol-Capped Oligonucleotides Bound to Gold Thin Films and Nanoparticles Analytical Chemistry. ,vol. 72, pp. 5535- 5541 ,(2000) , 10.1021/AC0006627
P. Alberti, J.-L. Mergny, DNA duplex–quadruplex exchange as the basis for a nanomolecular machine Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 1569- 1573 ,(2003) , 10.1073/PNAS.0335459100