Differential anxiety-like responses in NOD/ShiLtJ and C57BL/6J mice following experimental autoimmune encephalomyelitis induction and oral gavage.

作者: Pece Kocovski , Phuc T. Dang , Claretta S. D’Souza , Christopher E. Stamper , Matthew W. Hale

DOI: 10.1177/0023677218756156

关键词: PharmacologyNodExperimental autoimmune encephalomyelitisC57bl 6jAnxiety likeOral gavageElevated plus mazeAnxietyDrugMedicine

摘要: Oral gavage is commonly used in pre-clinical drug evaluation, but potentially aversive and may induce behavioral effects independent of compounds under investigation. This study examined the com...

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