Age-related susceptibility to Japanese encephalitis virus in domestic ducklings and chicks.

作者: Natalie B. Cleton , Michael J. Page , Richard A. Bowen , Angela Bosco-Lauth

DOI: 10.4269/AJTMH.13-0161

关键词: Weight gainOutbreakBiologyAge relatedVirologyViremiaVirusAnasJapanese encephalitisDisease reservoir

摘要: Ardeid birds and pigs are known as major amplifying hosts for Japanese encephalitis virus, ducklings chickens have been considered to play at best a minor role in outbreaks because of their low or absent viremia. We hypothesized that viremia sufficient magnitude would develop young (Anas platyrhynchos) chicks (Gallus gallus) them serve reservoir thereby contribute the transmission cycle. Infection was associated with reduced weight gain both species, infected 10 days age less showed overt clinical signs disease. The mean peak species decreased infection increased from 2 42 days, indicating importance on suggesting poultry may be disease-endemic regions.

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