Identification of a new member of the cytochrome P450 3A (CYP3A) gene family: CYP3AX
作者： Regina Eiselt , Klaus Gellner , Leszek Wojnowski
DOI:
关键词: Polynucleotide 、 Gene 、 Gene family 、 Transgene 、 Biology 、 Cytochrome P450 3A 、 Identification (biology) 、 Genetics 、 Computational biology 、 CYP3A
摘要: The present invention relates to polynucleotides encoding the CYP3AX protein and variants thereof. Further, also provides vectors comprising said polynucleotides, in particular vectors, wherein of are operatively linked regulatory elements allowing expression prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by antibodies specifically recognizing such proteins. concerns transgenic non-human animals above-described polynucleotide or vectors. Moreover, methods for identifying obtaining drug candidates inhibitors therapy disorders related malfunction genes as well diagnosing status disorders. identification molecular protein. furthermore pharmaceutical diagnostic compositions proteins, antibodies, drugs obtainable method. Said particularly useful treating various diseases with that substrates, modulators their product.
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