Increased incidence of Guillain-Barré syndrome after surgery.
作者： H. Gensicke , A. N. Datta , P. Dill , C. Schindler , D. Fischer
DOI: 10.1111/J.1468-1331.2012.03730.X
关键词: Risk factor 、 Cohort study 、 Retrospective cohort study 、 Attributable risk 、 Incidence (epidemiology) 、 Guillain-Barre syndrome 、 Pediatrics 、 Medicine 、 Surgery 、 Population study 、 Relative risk
摘要: BACKGROUND AND PURPOSE: Antecedent surgery has been described to trigger Guillain/x96Barre syndrome (GBS), but its evidence is poor and based on case reports only. METHODS: We performed a retrospective analysis of 63 patients with GBS admitted the University Hospital Basel Children's from January 2005 December 2010. calculated compared incidences post-surgical non-exposed in study population those reported previously literature. RESULTS: Six (9.5%) cases had within 6 weeks prior GBS. The relative risk developing during 6-week period after 13.1 times higher than normal incidence (95% confidence interval: 5.68, 30.3; P >/= 0.0001), suggesting an attributable 4.1 per 100 000 surgeries. In addition, significantly influenza vaccine-associated (P = 0.01) as well comparison previous 0.0001) background 0.0001). CONCLUSION: Surgery must be considered potential factor for
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