Therapeutic agent for muscular dystrophy

作者: Shinsuke. Yuasa , Keiichi. Fukuda

DOI:

关键词: Degeneration (medical)Physical medicine and rehabilitationMedicineBioinformaticsActive ingredientSkeletal muscleMuscular dystrophy

摘要: The present invention provides therapeutic agents for diseases associated with skeletal muscle degeneration comprising a granulocyte colony-stimulating factor (G-CSF) as an active ingredient. of the are especially effective muscular dystrophy.

参考文章(19)
Mirella Meregalli, Andrea Farini, Daniele Parolini, Simona Maciotta, Yvan Torrente, Stem cell therapies to treat muscular dystrophy: progress to date. BioDrugs. ,vol. 24, pp. 237- 247 ,(2010) , 10.2165/11534300-000000000-00000
Mie Hara, Shinsuke Yuasa, Keiichi Fukuda, Muscle repair promoter ,(2009)
Michael K. Richards, Fulu Liu, Hiromi Iwasaki, Koichi Akashi, Daniel C. Link, Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway. Blood. ,vol. 102, pp. 3562- 3568 ,(2003) , 10.1182/BLOOD-2003-02-0593
R.Mark Grady, Haibing Teng, Mia C Nichol, Jeanette C Cunningham, Robert S Wilkinson, Joshua R Sanes, Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin : A model for Duchenne muscular dystrophy Cell. ,vol. 90, pp. 729- 738 ,(1997) , 10.1016/S0092-8674(00)80533-4
Nicholas P. Evans, Sarah A. Misyak, John L. Robertson, Josep Bassaganya-Riera, Robert W. Grange, Dysregulated intracellular signaling and inflammatory gene expression during initial disease onset in Duchenne muscular dystrophy. American Journal of Physical Medicine & Rehabilitation. ,vol. 88, pp. 502- 522 ,(2009) , 10.1097/PHM.0B013E3181A5A24F
BIGARD, JANMOT, SANCHEZ, SERRURIER, POLLET, D’ALBIS, Changes in myosin heavy chain profile of mature regenerated muscle with endurance training in rat. Acta Physiologica Scandinavica. ,vol. 165, pp. 185- 192 ,(1999) , 10.1046/J.1365-201X.1999.00487.X
Anne E Deconinck, Jill A Rafael, Judith A Skinner, Susan C Brown, Allyson C Potter, Laurent Metzinger, Diana J Watt, J.George Dickson, Jonathon M Tinsley, Kay E Davies, Utrophin-Dystrophin-Deficient Mice as a Model for Duchenne Muscular Dystrophy Cell. ,vol. 90, pp. 717- 727 ,(1997) , 10.1016/S0092-8674(00)80532-2
Ioannis Stratos, Robert Rotter, Christian Eipel, Thomas Mittlmeier, Brigitte Vollmar, Granulocyte-colony stimulating factor enhances muscle proliferation and strength following skeletal muscle injury in rats Journal of Applied Physiology. ,vol. 103, pp. 1857- 1863 ,(2007) , 10.1152/JAPPLPHYSIOL.00066.2007