Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers
作者： Toni Weinschenk , Peter Lewandrowski , Harpreet Singh , Jens Fritsche , Steffen Walter
DOI:
关键词: Immune system 、 Immunology 、 Cancer vaccine 、 Epitope 、 Cell 、 Medicine 、 Peptide 、 Active ingredient 、 Immunotherapy 、 Cancer
摘要: The present invention relates to immunotherapeutic peptides and their use in immunotherapy, particular the immunotherapy of cancer. discloses tumor-associated T-helper cell peptide epitopes, alone or combination with other that serve as active pharmaceutical ingredients vaccine compositions which stimulate anti-tumor immune responses. In particular, composition can be used for eliciting responses against gastric cancers (GC).
lens.org参考文章(143)
M. Strubin, B. Mach, E.O. Long, The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarity. The EMBO Journal. ,vol. 3, pp. 869- 872 ,(1984) , 10.1002/J.1460-2075.1984.TB01898.X
Stefan Stevanović, Jutta Bachmann, Hans-Georg Rammensee, MHC Ligands and Peptide Motifs ,(1998)
Wretlind Arvid Johannes, Method of preparing intravenously injectable fat emulsions free from side reactions or complications ,(1961)
Germana Rappa, Oystein Fodstad, Aurelio Lorico, The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma Stem Cells. ,vol. 26, pp. 3008- 3017 ,(2008) , 10.1634/STEMCELLS.2008-0601
Cara M. Martin, Katharine Astbury, Lynda McEvoy, Sharon O'Toole, Orla Sheils, John J. O'Leary, Gene Expression Profiling in Cervical Cancer: Identification of Novel Markers for Disease Diagnosis and Therapy Methods in Molecular Biology. ,vol. 511, pp. 333- 359 ,(2009) , 10.1007/978-1-59745-447-6_15
H Grey, G Ishioka, F V Chisari, J Fikes, A Sette, C Crimi, B D Livingston, R W Chesnut, The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection. Journal of Immunology. ,vol. 159, pp. 1383- 1392 ,(1997)
Toni Weinschenk, Harpreet Singh, Oliver Schoor, Claudia Trautwein, Peter Lewandrowski, Norbert Hilf, Steffen Walter, Composition of tumour-associated peptides and related anti-cancer vaccine ,(2008)
Alfonso R. Gennaro, Remington: The Science and Practice of Pharmacy ,(2003)
Charles A. Nicolette, Bruce L. Roberts, Srinivas Shankara, Genes differentially expressed in cancer cells to design cancer vaccines ,(1999)
Nathaniel Gavin Nicholas Milton, Phosphorylated Amyloid-Beta 1-43 Protein and its use in the treatment of Alzheimer's disease ,(2001)