Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
作者： Stephen Newman , Rudolf Johannes Damhuis
DOI:
关键词: Fraction (chemistry) 、 Pharmaceutical formulation 、 Volume average 、 Chemistry 、 Lactose 、 Crystallography 、 Particle size 、 Chemical engineering
摘要: A process for forming lactose suitable use in a pharmaceutical formulation comprises providing plurality of particles containing no more than 10% w/w having volume average particle size about 70 microns or less; milling the to yield milled with an size, (D50), ranging from 50 100 microns; and classifying into at least two fractions comprising fine fraction coarse wherein has 3 microns, 40 250 microns.
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