Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
作者： Michael F. Clarke , Muhammad Al-Hajj
DOI:
关键词: Cancer cell 、 Cancer 、 Carcinogenesis 、 Metastasis 、 Bioinformatics 、 Breast cancer cells 、 Biology
摘要: The present invention relates to compositions and methods for characterizing, regulating, diagnosing, treating cancer. For example, the provides inhibiting tumorigenesis of certain classes cancer cells, including breast cells preventing metastasis. also systems identifying compounds that regulate tumorigenesis.
lens.org 参考文章(152)
Hendrik Uyttendaele, Jan Kitajewski, Angiogenic modulation by notch signal transduction ,(1999)
R. A. Reisfeld, S. Sell, Monoclonal antibodies and cancer therapy UCLA symposium on molecular and cellular biology. Annual meeting. 14. pp. 33- 74 ,(1985)
Hans Bundgaard, Design of prodrugs Elsevier , Sole distributors for the USA and Canada, Elsevier Science Pub. Co.. ,(1985)
Nancy B. Spinner, Ian D. Krantz, Leroy Hood, Linheng Li, Human jagged polypeptide, encoding nucleic acids and methods of use ,(1998)
E. Edward Baetge, Joseph P. Hammang, Samuel Weiss, Brent Reynolds, In vitro growth and proliferation of multipotent neural stem cells and their progeny ,(1995)
Andrew W. Shyjan, Murine gene fomy030 coding for tumor progression inhibitor ,(1995)
Yunsun Nam, Andrew P. Weng, Jon C. Aster, Stephen C. Blacklow, Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. Journal of Biological Chemistry. ,vol. 278, pp. 21232- 21239 ,(2003) , 10.1074/JBC.M301567200
Spyridon Artavanis-Tsakonas, Robert S. Mann, Grace E. Gray, Domingos Manuel Pinto Henrique, Robert J. Fleming, Julian Hart Lewis, David Ish-Horowicz, Anna Mary Myat, Protein sequences of serrate gene products ,(1996)
Duojia Pan, Gerald M. Rubin, Jenny Rooke, Reza Yavari, Tian Xu, KUZ, a novel family of metalloproteases ,(1997)
David J. Anderson, Derek L. Stemple, Immoralized neural crest stem cells and methods of making ,(1995)