System and method of measuring cell viability and growth

作者: Rasim Oytun Guldiken , Shyam S. Mohapatra , Rajesh R. Nair , Subhra Mohapatra

DOI:

关键词: Regeneration (biology)Cell biologyCell growthViability assayMass loadingCancer cellCell cultureStem cellBiologyBiosensor

摘要: A novel SH-SAW biosensor capable of non-invasive and touch-free detection cancer cell viability growth or proliferation in two-dimensional (2D) three-dimensional (3D) cultures as well stem regeneration it pertains to biology anti-cancer drug development is presented. The includes two pairs resonators including interdigital transducers reflecting fingers quantify mass loading by the cells suspension within a tumoroid culture platform. can be part perfused 3PNS-tumoroid system that amenable real-time monitoring proliferation, viability, multiplexed key physiologic clinical biomarkers.

参考文章(36)
Mengsu Yang, Chi Hung Tzang, Li Su, Pik Yuen Cheung, Piezoelectric ceramic sensor and sensor array for detection of molecular makers ,(2008)
Shyam S. Mohapatra, Subhra Mohapatra, Three-dimensional fibrous scaffolds for cell culture ,(2014)
o Genetel Pharmaceutical Limited Su, Pik Yuen c, Li c, Chi Hung c, o Genetel Pharmaceutical Limited Yang, Mengsu c, o Genetel Pharmaceuticals Limited Cheung, o Genetel Pharmaceutical Limited Tzang, Piezoelectric biosensor and biosensor array for parallel detection of multiple biomarkers ,(2007)
Kenneth A. Marx, Abiche H. Dewilde, Sai Liu, Hongwei Sun, Susan J. Braunhut, Jianping Zhang, Joel M. Therrien, Malavika Vashist, Lian Dai, Gang Wang, Acoustic wave (aw) sensing devices using live cells ,(2011)
Ioana Rodica Voiculescu, Anis Nurashikin Nordin, Muhammad Ibn Ibrahimy, Maizirwan Mel, Novel mems biosensor with integrated impedance and mass-sensing capabilities ,(2010)
Myeong Chan Jo, Rasim Guldiken, Active density-based separation using standing surface acoustic waves Sensors and Actuators A-physical. ,vol. 187, pp. 22- 28 ,(2012) , 10.1016/J.SNA.2012.08.020
Chi-Yen Shen, Shih-Yuan Liou, Surface acoustic wave gas monitor for ppm ammonia detection Sensors and Actuators B-chemical. ,vol. 131, pp. 673- 679 ,(2008) , 10.1016/J.SNB.2007.12.061
Samantha M. Hattersley, Deborah C. Sylvester, Charlotte E. Dyer, Nicholas D. Stafford, Stephen J. Haswell, John Greenman, A microfluidic system for testing the responses of head and neck squamous cell carcinoma tissue biopsies to treatment with chemotherapy drugs. Annals of Biomedical Engineering. ,vol. 40, pp. 1277- 1288 ,(2012) , 10.1007/S10439-011-0428-9
María-Isabel Rocha-Gaso, Carmen March-Iborra, Ángel Montoya-Baides, Antonio Arnau-Vives, Surface generated acoustic wave biosensors for the detection of pathogens: a review. Sensors. ,vol. 9, pp. 5740- 5769 ,(2009) , 10.3390/S90705740
Deepti D Deobagkar, Veena Limaye, Sweta Sinha, RDS Yadava, Acoustic wave immunosensing of Escherichia coli in water Sensors and Actuators B-chemical. ,vol. 104, pp. 85- 89 ,(2005) , 10.1016/J.SNB.2004.04.106