One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate.

作者: Hiroaki Okada

DOI: 10.1016/S0169-409X(97)00050-1

关键词: Lactic acidChemistryPLGAPharmacologyActive ingredientDrug carrierGlycolic acidBiodegradable polymerDosage formOrganic chemistryLeuprorelin

摘要: … , 1-month and 3-month release injectable msp of leuprorelin acetate are reviewed with respect to the biocompatibility and biodegradation of the polymers, preparation, drug release, and …

参考文章(119)
Yoshiki Hayashi, Sumie Yoshioka, Yukio Aso, Alain Li Wan Po, Tadao Terao, Entrapment of Proteins in Poly(L-Lactide) Microspheres Using Reversed Micelle Solvent Evaporation Pharmaceutical Research. ,vol. 11, pp. 337- 340 ,(1994) , 10.1023/A:1018936314861
James M. Wheeler, Judith D. Knittle, James D. Miller, Depot leuprolide versus danazol in treatment of women with symptomatic endometriosis. I. Efficacy results. American Journal of Obstetrics and Gynecology. ,vol. 167, pp. 1367- 1371 ,(1992) , 10.1016/S0002-9378(11)91718-9
Hiroaki Okada, Yayoi Inoue, Toshiro Heya, Hayao Ueno, Yasuaki Ogawa, Hajime Toguchi, Pharmacokinetics of once-a-month injectable microspheres of leuprolide acetate. Pharmaceutical Research. ,vol. 8, pp. 787- 791 ,(1991) , 10.1023/A:1015818504906
Friedman Aj, Hoffman Di, Miller Jd, Comite F, Browneller Rw, Treatment of leiomyomata uteri with leuprolide acetate depot: a double-blind, placebo-controlled, multicenter study. The Leuprolide Study Group. Obstetrics & Gynecology. ,vol. 77, pp. 720- 725 ,(1991)
James M. Anderson, Roger E. Marchant, Tissue Responses to Drug Delivery Systems Recent Advances in Drug Delivery Systems. pp. 23- 39 ,(1984) , 10.1007/978-1-4613-2745-5_3
S. Votano, G. B. Serra, G. B. Lafuenti, M. Colosimo, N. Garcea, V. Panetta, L. Agatensi, C. Romanini, Efficacy of leuprorelin acetate depot in symptomatic fibromatous uteri: the Italian Multicentre Trial. Clinical Therapeutics. ,vol. 14, pp. 57- 73 ,(1992)
Hajime TOGUCHI, Yasuaki OGAWA, Hiroaki OKADA, Masaki YAMAMOTO, [Once-a-month injectable microcapsules of leuprorelin acetate]. Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan. ,vol. 111, pp. 397- 409 ,(1991) , 10.1248/YAKUSHI1947.111.8_397
Jeffrey R. Nelson, Stephen L. Corson, Long-term management of adenomyosis with a gonadotropin-releasing hormone agonist: a case report Fertility and Sterility. ,vol. 59, pp. 441- 443 ,(1993) , 10.1016/S0015-0282(16)55704-5
H Ochs, U Winkler, H J Künzig, A E Schindler, K Bühler, D Mayer-Eichberger, L Mettler, H P Zahradnik, U Cirkel, H P Schneider, Experience with leuprorelin acetate depot in the treatment of fibroids: a German multicentre study. Clinical Therapeutics. ,vol. 14, pp. 37- 50 ,(1992)