Spectral, Thermal, and Antimicrobial Studies on the Copper(II), Zinc(II), Cadmium(II), and Mercury(II) Chelates of a New Antimetabolite–5-Dimethylaminomethyl-2-Thiouracil

摘要: Owing to the presence of multiple donor atoms such as N(1)H, C(2)SH, N(3), C(4)O, and CNC in newly synthesized antimetabolite, namely, 5-dimethylaminomethyl-2-thiouracil, preferences hetero-atoms for coordination with metal ions like Cu(II), Zn(II), Cd(II), Hg(II) were explored. The complexes isolated characterized by chemical analysis spectroscopic techniques. ligand behaves a bidentate/tetradentate chelating ligand. Invariably all complexes, one is soft C(2)SH. kinetic thermodynamic parameters thermal decomposition chelates evaluated using (Coats–Redfern) (Madhusudanan–Krishnan–Ninan) equations. antimicrobial studies show that copper(II) are more active than other complexes.