MEASUREMENT OF PLATELET ADHESIVENESS. A SIMPLE IN VITRO TECHNIQUE DEMONSTRATING AN ABNORMALITY IN VON WILLEBRAND'S DISEASE.
作者： Edwin W. Salzman
DOI: 10.5555/URI:PII:0022214363902257
关键词: Thrombasthenia 、 Platelet 、 Platelet adhesiveness 、 Anticoagulant 、 Hemostasis 、 Internal medicine 、 Heparin 、 Coagulation 、 Pathology 、 Endocrinology 、 Blood Platelet Disorders 、 Chemistry
摘要: Abstract The adhesiveness of human blood platelets has been measured by an in vitro technique which employs a short contact time and requires no anticoagulant before with foreign surface. Under these conditions, platelet is normal disorders coagulation patients receiving heparin but deficient thrombasthenia ion Willebrand's disease. When exposed to glass, time-consuming reaction occurs, manifested rise adhesiveness. This phenomenon calcium not blocked heparin. These observations are consistent the thesis that initial aggregation hemostasis dependent on coagulation.
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