Mechanisms of drug resistance in Leishmania
作者： M. Ouellette , B. Papadopoulou
DOI: 10.1016/0169-4758(93)90135-3
关键词: Drug resistance 、 Computational biology 、 Pharmacology 、 Biology 、 Drug 、 Leishmania 、 Protozoan parasite
摘要: … A better understanding of drug resistance, to try to cir… release from a panel of NC-substrates was measured in drug-… more recently been found in drug-resistant protozoan parasites 22. …
elsevier.com
sci-hub.se 参考文章(47)
B. Papadopoulou, G. Roy, M. Ouellette, A novel antifolate resistance gene on the amplified H circle of Leishmania. The EMBO Journal. ,vol. 11, pp. 3601- 3608 ,(1992) , 10.1002/J.1460-2075.1992.TB05444.X
J. C. Zomerdijk, M. Ouellette, A. L. ten Asbroek, R. Kieft, A. M. Bommer, C. E. Clayton, P. Borst, The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei. The EMBO Journal. ,vol. 9, pp. 2791- 2801 ,(1990) , 10.1002/J.1460-2075.1990.TB07467.X
H.L. Callahan, S.M. Beverley, A member of the aldoketo reductase family confers methotrexate resistance in Leishmania. Journal of Biological Chemistry. ,vol. 267, pp. 24165- 24168 ,(1992) , 10.1016/S0021-9258(18)35743-0
T C White, F Fase-Fowler, H van Luenen, J Calafat, P Borst, The H circles of Leishmania tarentolae are a unique amplifiable system of oligomeric DNAs associated with drug resistance. Journal of Biological Chemistry. ,vol. 263, pp. 16977- 16983 ,(1988) , 10.1016/S0021-9258(18)37486-6
T E Ellenberger, S M Beverley, Multiple drug resistance and conservative amplification of the H region in Leishmania major. Journal of Biological Chemistry. ,vol. 264, pp. 15094- 15103 ,(1989) , 10.1016/S0021-9258(18)63816-5
S Detke, G Chaudhuri, J A Kink, K P Chang, DNA amplification in tunicamycin-resistant Leishmania mexicana. Multicopies of a single 63-kilobase supercoiled molecule and their expression. Journal of Biological Chemistry. ,vol. 263, pp. 3418- 3424 ,(1988) , 10.1016/S0021-9258(18)69087-8
K Kaur, T Coons, K Emmett, B Ullman, Methotrexate-resistant Leishmania donovani genetically deficient in the folate-methotrexate transporter. Journal of Biological Chemistry. ,vol. 263, pp. 7020- 7028 ,(1988) , 10.1016/S0021-9258(18)68598-9
H.L. Callahan, S.M. Beverley, Heavy metal resistance: a new role for P-glycoproteins in Leishmania. Journal of Biological Chemistry. ,vol. 266, pp. 18427- 18430 ,(1991) , 10.1016/S0021-9258(18)55077-8
K Wilson, F R Collart, E Huberman, J R Stringer, B Ullman, Amplification and molecular cloning of the IMP dehydrogenase gene of Leishmania donovani. Journal of Biological Chemistry. ,vol. 266, pp. 1665- 1671 ,(1991) , 10.1016/S0021-9258(18)52346-2
X Liu, K P Chang, The 63-kilobase circular amplicon of tunicamycin-resistant Leishmania amazonensis contains a functional N-acetylglucosamine-1-phosphate transferase gene that can be used as a dominant selectable marker in transfection. Molecular and Cellular Biology. ,vol. 12, pp. 4112- 4122 ,(1992) , 10.1128/MCB.12.9.4112