Fibrinolytic activity in thrombosed veins.

摘要: Thrombosis of the femoral vein in rats was produced by injection thrombin, serum, or sodium morrhuate into ligated venous segments. The histologic effects were followed during resolution organization thrombus and correlated with appearance localization fibrinolytic activity as assayed histochemically. Lysis began immediately when thrombin serum had been used. Sites thrombolysis related to presence endothelial cells origin containing plasminogen activator. Sodium destroyed fibrinolytically active thus delaying thrombolysis. Recanalization associated locally cells, originating presumably adjacent normal endothelium. These results support previous observations on vascular They elucidate role played endothelium thrombi. also co...