An optimal culture medium for growing Karlodinium veneficum: Progress towards a microalgal dinoflagellate-based bioprocess
作者： L. López-Rosales , F. García-Camacho , A. Sánchez-Mirón , Yusuf Chisti
DOI: 10.1016/J.ALGAL.2015.05.006
关键词: Photobioreactor 、 Dinoflagellate 、 Cell concentration 、 Food science 、 Bioprocess 、 Botany 、 Karlodinium veneficum 、 Biology
摘要: Abstract In addressing a potential bioprocess for bioactives production from microalgae, the choice of proper culture medium is key factor. present work, an optimal producing marine dinoflagellate microalga Karlodinium veneficum was formulated using stochastic search strategy based on genetic algorithm. The optimized formulation had 25 components including macronutrients, trace elements and vitamins. With this medium, final attainable cell concentration during batch growth enhanced by 120% relative to control grown in L1 medium. titer bioactive karlotoxins measured hemolytic activity filtrate 190% control. These results are promising basis further development photobioreactor strategies microalgal dinoflagellates.
elsevier.com
sci-hub.se 参考文章(22)
Jiangnan Peng, Allen R. Place, Wesley Yoshida, Clemens Anklin, Mark T. Hamann, Structure and Absolute Configuration of Karlotoxin-2, an Ichthyotoxin from the Marine Dinoflagellate Karlodinium veneficum Journal of the American Chemical Society. ,vol. 132, pp. 3277- 3279 ,(2010) , 10.1021/JA9091853
F. Garcia Camacho, J. Gallardo Rodríguez, A. Sánchez Mirón, M.C. Cerón García, E.H. Belarbi, Y. Chisti, E. Molina Grima, Biotechnological significance of toxic marine dinoflagellates. Biotechnology Advances. ,vol. 25, pp. 176- 194 ,(2007) , 10.1016/J.BIOTECHADV.2006.11.008
J.J. Gallardo-Rodríguez, F. García-Camacho, A. Sánchez-Mirón, L. López-Rosales, Y. Chisti, E. Molina-Grima, Shear-induced changes in membrane fluidity during culture of a fragile dinoflagellate microalga Biotechnology Progress. ,vol. 28, pp. 467- 473 ,(2012) , 10.1002/BTPR.737
Tung-Yuan Ho, Antonietta Quigg, Zoe V. Finkel, Allen J. Milligan, Kevin Wyman, Paul G. Falkowski, Francois M. M. Morel, The elemental composition of some marine phytoplankton Journal of Phycology. ,vol. 39, pp. 1145- 1159 ,(2003) , 10.1111/J.0022-3646.2003.03-090.X
Steve Dagenais-Bellefeuille, David Morse, Putting the N in dinoflagellates. Frontiers in Microbiology. ,vol. 4, pp. 369- 369 ,(2013) , 10.3389/FMICB.2013.00369
F. García-Camacho, J.J. Gallardo-Rodríguez, A. Sánchez-Mirón, Y. Chisti, E. Molina-Grima, Genetic algorithm-based medium optimization for a toxic dinoflagellate microalga Harmful Algae. ,vol. 10, pp. 697- 701 ,(2011) , 10.1016/J.HAL.2011.05.005
Peter Harms, Yordan Kostov, Joseph A. French, Mohammed Soliman, M. Anjanappa, Arun Ram, Govind Rao, Design and Performance of a 24-Station High Throughput Microbioreactor Biotechnology and Bioengineering. ,vol. 93, pp. 6- 13 ,(2006) , 10.1002/BIT.20742
Ryan M. Van Wagoner, Jonathan R. Deeds, Masayuki Satake, Anthony A. Ribeiro, Allen R. Place, Jeffrey L.C. Wright, Isolation and characterization of karlotoxin 1, a new amphipathic toxin from Karlodinium veneficum. Tetrahedron Letters. ,vol. 49, pp. 6457- 6461 ,(2008) , 10.1016/J.TETLET.2008.08.103
L. López-Rosales, J.J. Gallardo-Rodríguez, A. Sánchez-Mirón, A. Contreras-Gómez, F. García-Camacho, E. Molina-Grima, Modelling of multi-nutrient interactions in growth of the dinoflagellate microalga Protoceratium reticulatum using artificial neural networks Bioresource Technology. ,vol. 146, pp. 682- 688 ,(2013) , 10.1016/J.BIORTECH.2013.07.141
Allen R. Place, Holly A. Bowers, Tsetvan R. Bachvaroff, Jason E. Adolf, Jonathan R. Deeds, Jian Sheng, Karlodinium veneficum—The little dinoflagellate with a big bite Harmful Algae. ,vol. 14, pp. 179- 195 ,(2012) , 10.1016/J.HAL.2011.10.021