作者: Paul S. Bernstein , Robert R. Rando
DOI: 10.1016/0076-6879(90)89327-E
关键词: Biochemistry 、 Isomerase 、 Retinoid isomerase 、 Visual phototransduction 、 Metabolism 、 Mechanism of action 、 Enzyme 、 Retinoic acid 、 Chemistry 、 Retinal isomerase
摘要: Publisher Summary The discovery and characterization of the retinoid isomerase have significant implications. It is an enzyme that completes a fundamental biochemical cycle apparently common to all vertebrate visual systems. also first known whose physiological task drive enzymatic conversion trans double bond higher energy cis configuration. This chapter describes methods used assay this important enzyme. clear isomerase, system bleaching dark adaptation, will role in physiology pathophysiology vision, as well providing insights into study enzymes general. Future purification novel class should clarify its relationship other enzymes, regulation, mechanism action.