Configuration Optimization and Mass Transfer in a Dual-Impeller Bioreactor

作者: Liangzhu Zu , Hongbao Zhou , Shifang Yang , Xiangyang Li , Chao Yang

DOI: 10.1252/JCEJ.14WE018

关键词: TurbineImpellerConfiguration optimizationSpargingAgitatorMaterials scienceChromatographyMass transferGas dispersionBioreactorAnalytical chemistry

摘要: The bioreactor configuration including a dual-impeller combination, spacing between the impellers, and diameter of ring sparger is optimized based on solid suspension (N-jsg) gas dispersion (N-f k(L)a) in this work. Then, performance are systematically studied. It found that smaller (D-s/T = 0.32) achieves better dispersion. A pitched-blade disc turbine down-pumping (PDTD) as bottom impeller lowest N-jsg value, has lower N-f value compared with PBTD (pitched blade down-pumping) TBHA (three-bladed helical agitator). Techmix 335 hydrofoil (TXD) an upper provides higher k(L)a values. TXD+PDTD more suitable for requirements bioreactor. decreases slightly increasing loading, which beneficial to good such bioleaching reactors loadings (>20 wt%).

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