Lymphatic Vascular Morphogenesis
作者： Florence Tatin , Taija Makinen
DOI: 10.1007/978-2-8178-0466-8_2
关键词: Immune system 、 Lymphatic Capillary 、 Tissue homeostasis 、 Lymphatic system 、 Pathology 、 Medicine 、 Inflammation 、 Lymphatic function 、 Lymphatic Endothelium 、 Lymphatic vessel
摘要: Lymphatic vessels participate in tissue homeostasis and immune surveillance by draining excess fluid cells from tissues to blood circulation. Impaired lymphatic function can lead swelling, or lymphoedema, associated complications, such as chronic inflammation fat accumulation. The critical role of a number pathological conditions, including tumour metastasis, has led an interest identifying signalling pathways regulating vessel development growth. Here, we review the current knowledge on molecular mechanisms how vasculature contributes diseases.
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