Drug-Loaded Lipid-Core Micelles in Mucoadhesive Films as a Novel Dosage Form for Buccal Administration of Poorly Water-Soluble and Biological Drugs.

作者: Wai-Houng Chou , Ariel Galaz , Miguel O. Jara , Alexander Gamboa , Javier O. Morales

DOI: 10.3390/PHARMACEUTICS12121168

关键词: MicelleIn vitroEx vivoPermeationChemistryRhodamine 123Dosage formBuccal administrationRhodamineChromatography

摘要: … transport rhodamine 123 and human insulin as models for poorly water-soluble and biological drugs, using lipid-core micelles … LCMs in suspension and free drugs in solution as controls…

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