Personal and occupational exposure to organic solvents and risk of non-Hodgkin's lymphoma (NHL) in women (United States).

摘要: Objectives: The authors assessed whether home and occupational exposure to organic solvents is associated with risk of NHL in women. Methods: A population-based, incidence case-control study was conducted upstate New York, involving 376 cases 463 population controls selected from the Medicare beneficiary files State driver’s license records. Exposure information obtained by telephone interview. Odds ratios (OR) 95% confidence intervals (CI) were estimated using an unconditional logistic regression model, adjusting for a number factors NHL. Results: Overall, history not statistically significant increase observed only subjects whose first occurred before 1970 (OR=1.87, CI 1.03–3.40). When exposures paint thinners/turpentine combined analyzed together, any exposure, compared no at either job or home, significantly increased (OR=1.46, CI: 1.05–2.03). This observation more pronounced B-cell lymphoma low-grade ORs 1.52 (95 1.08–2.14) 2.20 (95% CI; 1.42–3.41), respectively. Conclusions: results this do support major role development among women currently living US. However, relatively intensive past occupations use may deserve further investigation.