Graves’ Disease in Childhood

摘要: The most prevalent cause of thyrotoxicosis in children is Graves’ disease (GD), and remission occurs only a modest proportion patients. Thus pediatric patients with GD will need treatment radioactive iodine (RAI; 131I) or surgical thyroidectomy. When antithyroid drugs (ATDs) are prescribed, methimazole (MMI) should be administered, as PTU associated an unacceptable risk severe liver injury. If does not occur following ATD therapy, 131I surgery contemplated. dosages greater than 150 μCi/g thyroid tissue, higher needed for large glands. Considering that there low-level whole body radiation exposure 131I, this avoided young children. performed, near total thyroidectomy the recommended procedure. Complications considerably adults; thus experienced surgeon when operated on. Most importantly, care can complicated requires physicians expertise area.