A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133.

作者: Ines Liebscher , Julia Schön , Sarah C. Petersen , Liane Fischer , Nina Auerbach

DOI: 10.1016/J.CELREP.2014.11.036

关键词: Cell biologyAgonistPeptide sequenceBiochemistryGPR56EctodomainBiologySignal transductionG protein-coupled receptorReceptorG protein

摘要: … in zebrafish with a mutated Stachel sequence, and signaling is restored in hypomorphic gpr126 zebrafish … sequence as the “Stachel sequence” (Stachel is the German word for stinger). …

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