Homeopathy for treatment of irritable bowel syndrome

摘要: Background Irritable bowel syndrome (IBS) is a common, chronic disorder that leads to decreased health-related quality of life and work productivity. Evidence-based treatment guidelines have not been able give guidance on the effects homeopathic for IBS because no systematic reviews carried out assess effectiveness IBS. Two types were evaluated in this review. In clinical homeopathy specific remedy prescribed condition. This differs from individualised treatment, where based person's individual symptoms after detailed consultation. Objectives To safety treating IBS. Search methods We searched MEDLINE, Cochrane Central Register Controlled Trials, EMBASE, Cumulative Index Nursing Allied Health Literature (CINAHL), Complementary Medicine Database (AMED), IBD/FBD Group Specialised Register, Field database Homeopathic Library (Hom-inform) inception February 2013. Selection criteria Randomised controlled trials (RCTs), cohort case-control studies compared with placebo, other control treatments, or usual care, adults considered inclusion. Data collection analysis Two authors independently assessed risk bias extracted data. The primary outcome was global improvement overall evidence supporting using GRADE criteria. We calculated mean difference (MD) 95% confidence interval (CI) continuous outcomes ratio (RR) CI dichotomous outcomes. Main results Three RCTs (213 participants) included. No identified. published 1976 1979 (homeopathic remedy) placebo constipation-predominant One study 1990 (consultation plus care (defined as high doses dicyclomine hydrochloride, faecal bulking agents diet sheets asking patient take fibre diet) female patients. Due low reporting included all three unclear most criteria some A meta-analysis two small (129 participants IBS) found statistically significant between asafoetida at short-term follow-up weeks. Seventy-three per cent patients group improved 45% (RR 1.61, 1.18 2.18). There remedies nux vomica placebo. Sixty-eight 52% (1 study, N = 42, RR 1.31, 0.80 2.15). analyses rated very due unknown bias, sparse RCT, 20) "feeling unwell", participant scored how "unwell" they felt before, (MD 0.03; -3.16 3.22). None reported adverse events. Authors' conclusions A pooled analysis suggests possible benefit homeopathy, asafoetida, over people These results should be interpreted caution these trials, follow-up, advising diet). conclusions can drawn number trial. addition, it likely has changed since trial conducted. Further quality, adequately powered are required efficacy care.