Concordance between European and US case definitions of healthcare-associated infections

摘要: Surveillance of healthcare-associated infections (HAI) is a valuable measure to decrease infection rates. Across Europe, inter-country comparisons HAI rates seem limited because some countries use US definitions from the Centers for Disease Control and Prevention (CDC/NHSN) while other European Hospitals in Europe Link Infection through (HELICS/IPSE) project. In this study, we analyzed concordance between HAI. An international working group experts seven was set up identify differences then conduct surveillance using both sets during three-month period (March 1st -May 31st, 2010). Concordance case estimated with Cohen’s kappa statistic (κ). Differences were found bloodstream (BSI), pneumonia (PN), urinary tract (UTI) two key terms “intensive care unit (ICU)-acquired infection” “mechanical ventilation”. these exception UTI. performed 47 ICUs 6,506 patients assessed. One hundred eighty PN 123 BSI cases identified. When all considered, κ = 0.99 [CI 95%: 0.98-1.00]. divided into subgroups, κ = 0.90 (CI 0.86-0.94) clinically defined κ = 0.72 0.63-0.82) microbiologically PN. κ = 0.73 0.66-0.80]. However, secondary another site (42% cases) are excluded when κ = 1.00 only primary cases, i.e. Europe-defined ”catheter” or “unknown” origin US-defined laboratory-confirmed (LCBI), considered. Our study showed an excellent BSI. either can be compared if points highlighted taken account.