Serum Complement Sensitivity as a Key Factor in Lyme Disease Ecology

作者: Klaus Kurtenbach , Henna-Sisko Sewell , Nick H. Ogden , Sarah E. Randolph , Patricia A. Nuttall

DOI: 10.1128/IAI.66.3.1248-1251.1998

关键词: VirologyMicrobiologySpirochaetaceaeBorrelia lusitaniaeLyme borreliosisSensuEcologyBiologyLyme diseaseBorrelia burgdorferiSerum complementBorrelia

摘要: The sensitivity of Borrelia burgdorferi sensu lato to animal sera was analyzed. Complement-mediated borreliacidal effects were observed with particular combinations host serum and genospecies. species-specific pattern viability and/or lysis is highly consistent the reservoir competence hosts for B. lato, suggesting a key role complement in global ecology Lyme borreliosis.

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