Molecular and Cellular Aspects of Macrophage Aging
作者： Carlos Sebastián , Jorge Lloberas , Antonio Celada
DOI: 10.1007/978-1-4020-9063-9_46
关键词: Innate immune system 、 Inflammation 、 Acquired immune system 、 Immunosenescence 、 Immune system 、 Cell biology 、 Biology 、 Macrophage 、 Antigen 、 DNA damage
摘要: Macrophages are key cells in innate and adaptive immune function. These involved the destruction of bacteria, parasites, viruses tumor lead to initiation inflammatory process. In addition, macrophages responsible for processing antigens presenting digested peptides T-lymphocytes initiating response. Finally, participate resolution process by promoting tissue repair. Macrophage functions affected aging, thereby contributing immunosenescence immunity. Here, we summarize data about effects aging on discuss molecular events that could be this
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